产品货号：
Z21097
中文名称：
Mouse MELK抗体
英文名称：
Anti-Mouse MELK Antibody (C-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Mouse MELK Antibody (C-term) |
| 指标别名 | hMELK;HPK38;KIAA0175;MELK;Protein kinase PK38 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | WB,FCM |
| 基因名称 | Melk |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This mouse Melk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 434-468 amino acids from the C-terminal region of mouse Melk. |
| 计算分子量 | 73kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Serine/threonine-protein kinase involved in various processes such as cell cycle regulation,self-renewal of stem cells,apoptosis and splicing regulation.Has a broad substrate specificity;phosphorylates BCL2L14,CDC25B,MAP3K5/ASK1 and ZNF622.Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1.Acts as a regulator of cell cycle,notably by mediating phosphorylation of CDC25B,promoting localization of CDC25B to the centrosome and the spindle poles during mitosis.Plays a key role in cell proliferation.Required for proliferation of embryonic and postnatal multipotent neural progenitors.Phosphorylates and inhibits BCL2L14.Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622,thereby contributing to its redirection to the nucleus.May also play a role in primitive hematopoiesis. |
| Uniprot ID | Q61846 |
相关搜索：Mouse MELK抗体，Mouse MELK(C-term)多抗，Anti-Mouse MELK Antibody (C-term)